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Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis?

BACKGROUND: Recent studies have demonstrated a role for spinal p38 MAP kinase (MAPK) in the development of chronic inflammation and peripheral arthritis and a role for GABA in the inhibition of p38 MAPK mediated effects. Integrating these data suggests that GABA may play a role in downregulating mec...

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Hlavní autoři: Kelley, James M, Hughes, Laura B, Bridges, S Louis
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2235846/
https://ncbi.nlm.nih.gov/pubmed/18171484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-1
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