A Repressive Role for Prohibitin in Estrogen Signaling

Nuclear receptor-mediated gene expression is regulated by corepressors and coactivators. In this study we demonstrate that prohibitin (PHB), a potential tumor suppressor, functions as a potent transcriptional corepressor for estrogen receptor α (ERα). Overexpression of PHB inhibits ERα transcription...

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Détails bibliographiques
Auteurs principaux: He, Bin, Feng, Qin, Mukherjee, Atish, Lonard, David M., DeMayo, Francesco J., Katzenellenbogen, Benita S., Lydon, John P., O’Malley, Bert W.
Format: Artigo
Langue:Inglês
Publié: The Endocrine Society 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234581/
https://ncbi.nlm.nih.gov/pubmed/17932104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0400
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