ACETYLCHOLINE AND ITS THIOLESTER AND SELENOLESTER ANALOGS: CONFORMATION, ELECTRON DISTRIBUTION, AND BIOLOGICAL ACTIVITY

The crystal structures of acetylthiolcholine bromide and propionylthiolcholine iodide were elucidated. Acetylthiolcholine was found to be essentially isosteric with acetylselenolcholine, while the conformation of these compounds was quite different from that of acetylcholine. The importance of confo...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Shefter, Eli, Mautner, Henry G.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1969
Sujets:	Biological Sciences: Biochemistry
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5260928/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.63.4.1253
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