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COMPARED EFFECTS OF DITHIOTHREITOL ON THE INTERACTION OF AN AFFINITY-LABELING REAGENT WITH ACETYLCHOLINESTERASE AND THE EXCITABLE MEMBRANE OF THE ELECTROPLAX

p-(trimethyl ammonium) benzene diazonium difluoroborate (TDF), an affinity-labeling reagent of the acetylcholine receptor site(s), which in the normal cell acts as an irreversible inhibitor becomes a reversible activator after in vivo exposure of the electroplax to dithiothreitol (DTT), a disulfide...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Podleski, Thomas, Meunier, Jean-Claude, Changeux, Jean-Pierre
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1969
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223456/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5260926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.63.4.1239
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