High blood pressure reduction reverses angiotensin II type 2 receptor-mediated vasoconstriction into vasodilation in spontaneously hypertensive rats.

BACKGROUND: We have previously shown that angiotensin II type 2 receptor (AT(2)R) stimulation causes endothelium-dependent vasodilation which does not desensitize after chronic angiotensin II type 1 receptor (AT(1)R) blockade, suggesting a role for AT(2)R in antihypertensive treatment. MATERIAL AND...

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Autori principali: You, Dong, Loufrani, Laurent, Baron, Céline, Levy, Bernard I., Widdop, Robert E., Henrion, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2005
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234478/
https://ncbi.nlm.nih.gov/pubmed/15710752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000156503.62815.48
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