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Human CMV infection induces 5-lipoxygenase expression and leukotriene B(4) production in vascular smooth muscle cells

Leukotrienes (LTs) are powerful proinflammatory lipid mediators that may play a central role in cardiovascular diseases, including arteriosclerosis, myocardial infarction, and stroke. Owing to restricted expression of 5-lipoxygenase (5-LO), the enzyme required for their synthesis, LTs are almost exc...

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Detalhes bibliográficos
Main Authors: Qiu, Hong, Strååt, Klas, Rahbar, Afsar, Wan, Min, Söderberg-Nauclér, Cecilia, Haeggström, Jesper Z.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234367/
https://ncbi.nlm.nih.gov/pubmed/18180307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070201
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