Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease

Celiac disease (CD) is an enteropathy resulting from an abnormal immune response to gluten-derived peptides in genetically susceptible individuals. This immune response is initiated by intestinal transport of intact peptide 31-49 (p31-49) and 33-mer gliadin peptides through an unknown mechanism. We...

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Main Authors: Matysiak-Budnik, Tamara, Moura, Ivan Cruz, Arcos-Fajardo, Michelle, Lebreton, Corinne, Ménard, Sandrine, Candalh, Céline, Ben-Khalifa, Karima, Dugave, Christophe, Tamouza, Houda, van Niel, Guillaume, Bouhnik, Yoram, Lamarque, Dominique, Chaussade, Stanislas, Malamut, Georgia, Cellier, Christophe, Cerf-Bensussan, Nadine, Monteiro, Renato C., Heyman, Martine
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234361/
https://ncbi.nlm.nih.gov/pubmed/18166587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071204
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