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Mutations in Hydin impair ciliary motility in mice

Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility, and mice with Hydin defects develop lethal hydrocephalus. To determine if defects in Hydin cause hydrocephalus through a mechanism involving cilia, we compared the morphology, ultrastructure, and activity of c...

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Main Authors: Lechtreck, Karl-Ferdinand, Delmotte, Philippe, Robinson, Michael L., Sanderson, Michael J., Witman, George B.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234243/
https://ncbi.nlm.nih.gov/pubmed/18250199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710162
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