Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo

Correct positioning and morphology of the mitotic spindle is achieved through regulating the interaction between microtubules (MTs) and cortical actin. Here we find that, in the Drosophila melanogaster early embryo, reduced levels of the protein kinase Akt result in incomplete centrosome migration a...

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Bibliographic Details
Main Authors: Buttrick, Graham J., Beaumont, Luke M.A., Leitch, Jessica, Yau, Christopher, Hughes, Julian R., Wakefield, James G.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234228/
https://ncbi.nlm.nih.gov/pubmed/18268102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705085
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