Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo

Correct positioning and morphology of the mitotic spindle is achieved through regulating the interaction between microtubules (MTs) and cortical actin. Here we find that, in the Drosophila melanogaster early embryo, reduced levels of the protein kinase Akt result in incomplete centrosome migration a...

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Bibliografiske detaljer
Main Authors: Buttrick, Graham J., Beaumont, Luke M.A., Leitch, Jessica, Yau, Christopher, Hughes, Julian R., Wakefield, James G.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234228/
https://ncbi.nlm.nih.gov/pubmed/18268102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705085
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