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Heat-shock protein 90 associates with N-terminal extended peptides and is required for direct and indirect antigen presentation
CD8(+) T cells recognize peptide fragments of endogenously synthesized antigens of cancers or viruses, presented by MHC I molecules. Such antigen presentation requires the generation of peptides in the cytosol, their passage to the endoplasmic reticulum, loading of MHC I with peptides, and transport...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234201/ https://ncbi.nlm.nih.gov/pubmed/18216248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711365105 |
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