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Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity

Natural killer (NK) cells are important early mediators of host immunity to viral infections. The NK activatory receptors NKG2D and NKp80, both C-type lectin-like homodimeric receptors, stimulate NK cell cytotoxicity toward target cells. Like other herpesviruses, Kaposi's sarcoma-associated her...

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Detalhes bibliográficos
Main Authors: Thomas, Mair, Boname, Jessica M., Field, Sarah, Nejentsev, Sergey, Salio, Mariolina, Cerundolo, Vincenzo, Wills, Mark, Lehner, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234200/
https://ncbi.nlm.nih.gov/pubmed/18230726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707883105
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