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The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7

Polyglutamine diseases are inherited neurodegenerative disorders caused by expansion of CAG repeats encoding a glutamine tract in the disease-causing proteins. There are nine disorders, each having distinct features but also clinical and pathological similarities. In particular, spinocerebellar atax...

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書誌詳細
主要な著者: Gatchel, Jennifer R., Watase, Kei, Thaller, Christina, Carson, James P., Jafar-Nejad, Paymaan, Shaw, Chad, Zu, Tao, Orr, Harry T., Zoghbi, Huda Y.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234131/
https://ncbi.nlm.nih.gov/pubmed/18216249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711257105
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