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Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

Several members of the Rubiaceae and Violaceae plant families produce a series of cyclotides or macrocyclic peptides of 28–37 aa with an embedded cystine knot. The cyclic peptide backbone together with the knotted and strongly braced structure confers exceptional chemical and biological stability th...

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Bibliografiske detaljer
Main Authors: Barbeta, Barbara L., Marshall, Alan T., Gillon, Amanda D., Craik, David J., Anderson, Marilyn A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234119/
https://ncbi.nlm.nih.gov/pubmed/18202177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710338104
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