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Unique elastic properties of the spectrin tetramer as revealed by multiscale coarse-grained modeling

The force-extension profile of tetrameric spectrin is determined by using multiscale computer simulation. Fluctuation results of atomistic simulations of double spectrin repeat units (DSRU) are used to systematically build a coarse-grained (CG) model for the tetrameric form of spectrin. It is found...

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Bibliographische Detailangaben
Hauptverfasser: Mirijanian, Dina T., Voth, Gregory A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234116/
https://ncbi.nlm.nih.gov/pubmed/18202182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707500105
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