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The LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis
The oncogene latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) without a ligand drives proliferation of EBV-infected B cells. Its levels vary in cells of clonal populations by more than 100-fold, which leads to multiple distinct activities of the oncogene. At intermediate levels it drives...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234060/ https://ncbi.nlm.nih.gov/pubmed/18042799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-100032 |
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