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Dynamics of Ca(2+)-Calmodulin–dependent Inhibition of Rod Cyclic Nucleotide-gated Channels Measured by Patch-clamp Fluorometry

Cyclic nucleotide-gated (CNG) ion channels mediate cellular responses to sensory stimuli. In vertebrate photoreceptors, CNG channels respond to the light-induced decrease in cGMP by closing an ion-conducting pore that is permeable to cations, including Ca(2+) ions. Rod CNG channels are directly inhi...

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Main Authors: Trudeau, Matthew C., Zagotta, William N.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233886/
https://ncbi.nlm.nih.gov/pubmed/15314069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409101
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