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Inward Rectification in ClC-0 Chloride Channels Caused by Mutations in Several Protein Regions

Several cloned ClC-type Cl(−) channels open and close in a voltage-dependent manner. The Torpedo electric organ Cl(−) channel, ClC-0, is the best studied member of this gene family. ClC-0 is gated by a fast and a slow gating mechanism of opposite voltage direction. Fast gating is dependent on voltag...

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Autors principals: Ludewig, Uwe, Jentsch, Thomas J., Pusch, Michael
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233784/
https://ncbi.nlm.nih.gov/pubmed/9236209
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