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X Chromosome Activity in Mouse XX Primordial Germ Cells
In the early epiblast of female mice, one of the two X chromosomes is randomly inactivated by a Xist-dependent mechanism, involving the recruitment of Ezh2-Eed and the subsequent trimethylation of histone 3 on lysine 27 (H3K27me3). We demonstrate that this random inactivation process applies also to...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2233679/ https://ncbi.nlm.nih.gov/pubmed/18266475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0040030 |
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