SOLID PHASE SYNTHESIS OF A 42-RESIDUE FRAGMENT OF STAPHYLOCOCCAL NUCLEASE: PROPERTIES OF A SEMISYNTHETIC ENZYME

The polypeptide corresponding to the amino acid sequence from residue 6 through 47 in staphylococcal nuclease has been synthesized by the solid-phase method. The synthetic product closely resembles the corresponding native polypeptide in both physical and chemical properties. The synthetic peptide m...

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Bibliographic Details
Main Authors: Ontjes, David A., Anfinsen, Christian B.
Format: Artigo
Language:Inglês
Published: 1969
Subjects:
Physical Sciences: Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC223360/
https://ncbi.nlm.nih.gov/pubmed/5261024
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