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MITOTIC ABNORMALITIES IN SEA URCHIN EMBRYOS EXPOSED TO DACTINOMYCIN

Dactinomycin at concentrations of 10, 20, 25, and 50 μg/ml causes mitotic abnormalities in sea urchin embryos. Sister chromosome separation is impaired and anaphase bridges are frequently formed. The result is an unequal distribution of the chromosome complement to daughter cells. Possible explanati...

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Bibliographic Details
Main Authors: Kiefer, Barry I., Entelis, Charles F., Infante, Anthony A.
Format: Artigo
Language:Inglês
Published: 1969
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC223313/
https://ncbi.nlm.nih.gov/pubmed/4905991
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