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THE ROLE OF RIBOSOMAL CONFORMATION IN PROTEIN BIOSYNTHESIS: THE STREPTOMYCIN-RIBOSOME INTERACTION

The role played by ribosomal conformation in codon-anticodon recognition has been studied using streptomycin as a probe, inasmuch as streptomycin is known to cause misreading of the genetic code. Changes in ribosomal structure have been followed by the method of hydrogen-tritium exchange. The result...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sherman, Michael I., Simpson, Melvin V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1969
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223297/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4916926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.64.4.1388
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