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Localization and Molecular Determinants of the Hanatoxin Receptors on the Voltage-Sensing Domains of a K(+) Channel

Hanatoxin inhibits voltage-gated K(+) channels by modifying the energetics of activation. We studied the molecular determinants and physical location of the Hanatoxin receptors on the drk1 voltage-gated K(+) channel. First, we made multiple substitutions at three previously identified positions in t...

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Bibliographic Details
Main Authors: Li-Smerin, Yingying, Swartz, Kenton J.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2232886/
https://ncbi.nlm.nih.gov/pubmed/10828242
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