Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina

Recombinant adeno-associated virus (rAAV) is a promising vector for therapy of retinal degenerative diseases. We evaluated the efficiency, cellular specificity, and safety of retinal cell transduction in nonhuman primates after subretinal delivery of an rAAV carrying a cDNA encoding green fluorescen...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Bennett, Jean, Maguire, Albert M., Cideciyan, Artur V., Schnell, Michael, Glover, Ernest, Anand, Vibha, Aleman, Tomas S., Chirmule, Narendra, Gupta, Abha R., Huang, Yijun, Gao, Guang-Ping, Nyberg, William C., Tazelaar, John, Hughes, Joseph, Wilson, James M., Jacobson, Samuel G.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1999
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22311/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9920
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