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Cannabinoids decrease excitatory synaptic transmission and impair long-term depression in rat cerebellar Purkinje cells

1. CB-1 cannabinoid receptors are strongly expressed in the molecular layer of the cerebellar cortex. We have analysed, in patch-clamped Purkinje cells (PCs) in rat cerebellar slices, the effect of the selective CB-1 agonists WIN55,212-2 and CP55,940 and of the selective CB-1 antagonist SR141716-A o...

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Autors principals: Lévénès, Carole, Daniel, Hervé, Soubrié, Philippe, Crépel, Françis
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231086/
https://ncbi.nlm.nih.gov/pubmed/9660899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.867bj.x
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