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Ionotropic and metabotropic activation of a neuronal chloride channel by serotonin and dopamine in the leech Hirudo medicinalis

1. Cl(−) channels on the pressure-sensitive (P) neuron in the leech are directly activated by synaptic release of serotonin (5-HT) and are indirectly stimulated by the cAMP second messenger pathway, suggesting an unusual dual regulation of the channels. We have investigated the mode of action of 5-H...

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Autors principals: Ali, Declan W, Catarsi, Stefano, Drapeau, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230933/
https://ncbi.nlm.nih.gov/pubmed/9547394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.211bo.x
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