Role of the NO-cGMP pathway in the muscarinic regulation of the L-type Ca(2+) current in human atrial myocytes

1. The whole-cell patch-clamp technique was used to examine the participation of nitric oxide synthase (NOS) and soluble guanylyl cyclase in the muscarinic regulation of the L-type Ca(2+) current (I(Ca)) in freshly isolated human atrial myocytes. 2. Acetylcholine (ACh, 1 μM) decreased basal I(Ca) by...

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Autores principales: Vandecasteele, Grégoire, Eschenhagen, Thomas, Fischmeister, Rodolphe
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1998
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230739/
https://ncbi.nlm.nih.gov/pubmed/9503328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.653bv.x
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