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Intracellular Mg(2+) interacts with structural determinants of the narrow constriction contributed by the NR1-subunit in the NMDA receptor channel

1. N-methyl-D-aspartate (NMDA) receptor channels are blocked by intracellular Mg(2+) in a voltage-dependent manner. Amino acid residues positioned at or near the narrow constriction that interact with intracellular Mg(2+) were identified in recombinant NR1-NR2A channels expressed in Xenopus oocytes...

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Main Authors: Wollmuth, Lonnie P, Kuner, Thomas, Sakmann, Bert
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230705/
https://ncbi.nlm.nih.gov/pubmed/9481671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.00033.x
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