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Cystic Fibrosis Transmembrane Conductance Regulator: Physical Basis for Lyotropic Anion Selectivity Patterns

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl channel exhibits lyotropic anion selectivity. Anions that are more readily dehydrated than Cl exhibit permeability ratios (P (S)/P (Cl)) greater than unity and also bind more tightly in the channel. We compared the selectivity of CFTR...

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Bibliografiske detaljer
Main Authors: Smith, Stephen S., Steinle, Erich D., Meyerhoff, Mark E., Dawson, David C.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230651/
https://ncbi.nlm.nih.gov/pubmed/10578016
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