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Calcium Wave Propagation in Pancreatic Acinar Cells: Functional Interaction of Inositol 1,4,5-Trisphosphate Receptors, Ryanodine Receptors, and Mitochondria
In pancreatic acinar cells, inositol 1,4,5-trisphosphate (InsP(3))–dependent cytosolic calcium ([Ca(2+)](i)) increases resulting from agonist stimulation are initiated in an apical “trigger zone,” where the vast majority of InsP(3) receptors (InsP(3)R) are localized. At threshold stimulation, [Ca(2+...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2230627/ https://ncbi.nlm.nih.gov/pubmed/11004204 |
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