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Ion Interactions in the High-Affinity Binding Locus of a Voltage-Gated Ca(2+) Channel

The selectivity filter of voltage-gated Ca(2+) channels is in part composed of four Glu residues, termed the EEEE locus. Ion selectivity in Ca(2+) channels is based on interactions between permeant ions and the EEEE locus: in a mixture of ions, all of which can pass through the pore when present alo...

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Bibliographic Details
Main Authors: Cloues, Robin K., Cibulsky, Susan M., Sather, William A.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230626/
https://ncbi.nlm.nih.gov/pubmed/11004206
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