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Divergent Regulation of Protein Synthesis in the Cytosol and Endoplasmic Reticulum Compartments of Mammalian Cells

In eukaryotic cells, mRNAs encoding signal sequence-bearing proteins undergo translation-dependent trafficking to the endoplasmic reticulum (ER), thereby restricting secretory and integral membrane protein synthesis to the ER compartment. However, recent studies demonstrating that mRNAs encoding cyt...

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Detalhes bibliográficos
Main Authors: Stephens, Samuel B., Nicchitta, Christopher V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230589/
https://ncbi.nlm.nih.gov/pubmed/18077556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-07-0677
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