A Human Bone Morphogenetic Protein Antagonist Is Down-Regulated in Renal Cancer

We analyzed expression of candidate genes encoding cell surface or secreted proteins in normal kidney and kidney cancer. This screen identified a bone morphogenetic protein (BMP) antagonist, SOSTDC1 (sclerostin domain–containing-1) as down-regulated in kidney tumors. To confirm screening results, we...

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Main Authors: Blish, Kimberly Rose, Wang, Wei, Willingham, Mark C., Du, Wei, Birse, Charles E., Krishnan, Surekha R., Brown, Julie C., Hawkins, Gregory A., Garvin, A. Julian, D'Agostino, Ralph B., Torti, Frank M., Torti, Suzy V.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230586/
https://ncbi.nlm.nih.gov/pubmed/18032587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-05-0433
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