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Inflammatory mediators regulate cathepsin S in macrophages and microglia: A role in attenuating heparan sulfate interactions.

BACKGROUND: Cathepsin S is a member of the family of cysteine lysosomal proteases. The distribution of cathepsin S is restricted to cells from the mononuclear lineage both in the brain and in the periphery. Also, its protease activity is uniquely stable at neutral pH. MATERIALS AND METHODS: We compa...

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Autors principals: Liuzzo, J. P., Petanceska, S. S., Moscatelli, D., Devi, L. A.
Format: Artigo
Idioma:Inglês
Publicat: The Feinstein Institute for Medical Research 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230418/
https://ncbi.nlm.nih.gov/pubmed/10390548
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