Susceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3, -B8, -A1 haplotypes.

BACKGROUND: A common genetic basis for IgA deficiency (IgAD) and common variable immunodeficiency (CVID) is suggested by their occurrence in members of the same family and the similarity of the underlying B cell differentiation defects. An association between IgAD/CVID and HLA alleles DR3, B8, and A...

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Autori principali: Schroeder, H. W., Zhu, Z. B., March, R. E., Campbell, R. D., Berney, S. M., Nedospasov, S. A., Turetskaya, R. L., Atkinson, T. P., Go, R. C., Cooper, M. D., Volanakis, J. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Feinstein Institute for Medical Research 1998
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230309/
https://ncbi.nlm.nih.gov/pubmed/9508785
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