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Lipopolysaccharide-induced cytokine cascade and lethality in LT alpha/TNF alpha-deficient mice.

BACKGROUND: Tumor necrosis factor alpha (TNF-alpha) is often considered the main proinflammatory cytokine induced by lipopolysaccharide (LPS) and consequently the critical mediator of the lethality associated with septic shock. MATERIALS AND METHODS: We used mice carrying a deletion of both the lymp...

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Hlavní autoři: Amiot, F., Fitting, C., Tracey, K. J., Cavaillon, J. M., Dautry, F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Feinstein Institute for Medical Research 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230288/
https://ncbi.nlm.nih.gov/pubmed/9440119
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