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The role of a single formin isoform in the limb and renal phenotypes of limb deformity.

BACKGROUND: Mutations of the murine limb deformity (ld) locus are responsible for a pleiotropic phenotype of completely penetrant limb malformations and incompletely penetrant renal agenesis and/or dysgenesis. The ld locus encodes a complex family of mRNA and protein isoforms. MATERIALS AND METHODS:...

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Detalhes bibliográficos
Main Authors: Wynshaw-Boris, A., Ryan, G., Deng, C. X., Chan, D. C., Jackson-Grusby, L., Larson, D., Dunmore, J. H., Leder, P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute for Medical Research 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230207/
https://ncbi.nlm.nih.gov/pubmed/9234242
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