The non-ligand binding beta-isoform of the human glucocorticoid receptor (hGR beta): tissue levels, mechanism of action, and potential physiologic role.

BACKGROUND: Alternative splicing of the transcripts of the human glucocorticoid receptor gene results in two mutually exclusive products, the classic, ligand-binding glucocorticoid receptor (hGR alpha), and a dominant negative non-ligand-binding isoform, hGR beta. MATERIALS AND METHODS: We examined...

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Main Authors: de Castro, M., Elliot, S., Kino, T., Bamberger, C., Karl, M., Webster, E., Chrousos, G. P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute for Medical Research 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230188/
https://ncbi.nlm.nih.gov/pubmed/8898375
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