Overexpression of select T cell receptor V beta gene families within CD4+ and CD8+ T cell subsets of myasthenia gravis patients: a role for superantigen(s)?

BACKGROUND: The principal symptoms of myasthenia gravis (MG), muscle weakness and fatigue due to impaired neuromuscular transmission, are caused by autoantibodies to the muscle nicotinic acetylcholine receptor (AChR). The mechanisms underlying the autoimmune response, however, appear to be initiated...

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Autores principales: Gigliotti, D., Lefvert, A. K., Jeddi-Tehrani, M., Esin, S., Hodara, V., Pirskanen, R., Wigzell, H., Andersson, R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Feinstein Institute for Medical Research 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230170/
https://ncbi.nlm.nih.gov/pubmed/8827715
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