CD3-epsilon overexpressed in prothymocytes acts as an oncogene.

BACKGROUND: Upon engagement of the T cell receptor for antigen, its associated CD3 proteins recruit signal transduction molecules, which in turn regulate T lymphocyte proliferation, apoptosis, and thymocyte development. Because some signal transducing molecules recruited by CD3-epsilon, i.e., p56lck...

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Auteurs principaux: Wang, B., She, J., Salio, M., Allen, D., Lacy, E., Lonberg, N., Terhorst, C.
Format: Artigo
Langue:Inglês
Publié: The Feinstein Institute for Medical Research 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230102/
https://ncbi.nlm.nih.gov/pubmed/9132282
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