Inhibition of vascular smooth muscle cell proliferation and intimal hyperplasia by gene transfer of beta-interferon.

BACKGROUND: Balloon injury of the arterial wall induces increased vascular smooth cell proliferation, enhanced elastic recoil, and abnormalities in thrombosis, each of which contribute to regrowth of intima and the lesion of restenosis. Several gene transfer approaches have been used to inhibit such...

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Bibliographic Details
Main Authors: Stephan, D., San, H., Yang, Z. Y., Gordon, D., Goelz, S., Nabel, G. J., Nabel, E. G.
Format: Artigo
Language:Inglês
Published: The Feinstein Institute for Medical Research 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230084/
https://ncbi.nlm.nih.gov/pubmed/9323710
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