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Reduction of food intake and weight gain by the ob protein requires a specific secondary structure and is reversible.

BACKGROUND: Obesity, the condition of excessive accumulation of fat is a poorly understood disorder and is a risk factor for type II diabetes, hypertension, and hyperlipidaemia. Recently, a putative mouse obese gene was cloned and its product, termed ob protein, was shown to be involved in the regul...

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Detalhes bibliográficos
Main Authors: Giese, K., Fantl, W. J., Vitt, C., Stephans, J. C., Cousens, L., Wachowicz, M., Williams, L. T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute for Medical Research 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230025/
https://ncbi.nlm.nih.gov/pubmed/8900534
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