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Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus.

BACKGROUND: It has previously been observed that the insulin-producing cells of human pancreatic islets are more resistant to alloxan-, streptozotocin-, nitroprusside-, or cytokine-induced injury than those of mouse and rat islets. MATERIALS AND METHODS: Human pancreatic islets were obtained from he...

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Main Authors: Welsh, N., Margulis, B., Borg, L. A., Wiklund, H. J., Saldeen, J., Flodström, M., Mello, M. A., Andersson, A., Pipeleers, D. G., Hellerström, C.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230012/
https://ncbi.nlm.nih.gov/pubmed/8612203
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