Oligoclonality in the human CD8+ T cell repertoire in normal subjects and monozygotic twins: implications for studies of infectious and autoimmune diseases.

BACKGROUND: We have previously demonstrated CD8+ T cell clonal dominance using a PCR assay for the CDR3 length of T cell receptors belonging to a limited number of TCRBV segments/families. In this study, we have modified this approach in order to analyze more comprehensively the frequency of oligocl...

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Autors principals: Monteiro, J., Hingorani, R., Choi, I. H., Silver, J., Pergolizzi, R., Gregersen, P. K.
Format: Artigo
Idioma:Inglês
Publicat: The Feinstein Institute for Medical Research 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229970/
https://ncbi.nlm.nih.gov/pubmed/8529128
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