Nerve growth factor prevents both neuroretinal programmed cell death and capillary pathology in experimental diabetes.

BACKGROUND: Chronic diabetes causes structural changes in the retinal capillaries of nearly all patients with a disease duration of more than 15 years. Acellular occluded vessels cause hypoxia, which stimulates sight-threatening abnormal angiogenesis in 50% of all type I diabetic patients. The mecha...

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Main Authors: Hammes, H. P., Federoff, H. J., Brownlee, M.
Format: Artigo
Jezik:Inglês
Izdano: The Feinstein Institute for Medical Research 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229962/
https://ncbi.nlm.nih.gov/pubmed/8529118
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