Ciliary neurotrophic factor inhibits brain and peripheral tumor necrosis factor production and, when coadministered with its soluble receptor, protects mice from lipopolysaccharide toxicity.

BACKGROUND: The receptor of ciliary neurotrophic factor (CNTF) contains the signal transduction protein gp130, which is also a component of the receptors of cytokines such as interleukin (IL)-6, leukemia-inhibitory factor (LIF), IL-11, and oncostatin M. This suggests that these cytokines might share...

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Main Authors: Benigni, F., Villa, P., Demitri, M. T., Sacco, S., Sipe, J. D., Lagunowich, L., Panayotatos, N., Ghezzi, P.
Format: Artigo
Jezik:Inglês
Izdano: The Feinstein Institute for Medical Research 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229956/
https://ncbi.nlm.nih.gov/pubmed/8529123
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