Analysis of families at risk for insulin-dependent diabetes mellitus reveals that HLA antigens influence progression to clinical disease.

BACKGROUND: Individuals at risk for insulin-dependent diabetes mellitus (IDDM), with an affected first-degree relative, can be identified by the presence of islet cell antibodies (ICA). ICA-positive relatives progress at variable rates to IDDM and identification of those at highest risk is a prerequ...

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Main Authors: Honeyman, M. C., Harrison, L. C., Drummond, B., Colman, P. G., Tait, B. D.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229954/
https://ncbi.nlm.nih.gov/pubmed/8529124
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