טוען...

Regulation of K(+) Flow by a Ring of Negative Charges in the Outer Pore of BK(Ca) Channels. Part II: Neutralization of Aspartate 292 Reduces Long Channel Openings and Gating Current Slow Component

Neutralization of the aspartate near the selectivity filter in the GYGD pore sequence (D292N) of the voltage- and Ca(2+)-activated K(+) channel (MaxiK, BKCa) does not prevent conduction like the corresponding mutation in Shaker channel, but profoundly affects major biophysical properties of the chan...

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מידע ביבליוגרפי
Main Authors: Haug, Trude, Olcese, Riccardo, Toro, Ligia, Stefani, Enrico
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229619/
https://ncbi.nlm.nih.gov/pubmed/15277579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308950
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