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Gat1 (Gaba:Na(+):Cl(−)) Cotransport Function: Kinetic Studies in Giant Xenopus Oocyte Membrane Patches

To explain cotransport function, the “alternating access” model requires that conformational changes of the empty transporter allow substrates to bind alternatively on opposite membrane sides. To test this principle for the GAT1 (GABA:Na(+):Cl(−)) cotransporter, we have analyzed how its charge-movin...

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Bibliografske podrobnosti
Main Authors: Lu, Chin-Chih, Hilgemann, Donald W.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229455/
https://ncbi.nlm.nih.gov/pubmed/10469734
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