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Submaximal Responses in Calcium-triggered Exocytosis Are Explained by Differences in the Calcium Sensitivity of Individual Secretory Vesicles

A graded response to calcium is the defining feature of calcium-regulated exocytosis. That is, there exist calcium concentrations that elicit submaximal exocytotic responses in which only a fraction of the available population of secretory vesicles fuse. The role of calcium-dependent inactivation in...

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Autori principali: Blank, Paul S., Cho, Myoung-Soon, Vogel, Steven S., Kaplan, Doron, Kang, Albert, Malley, James, Zimmerberg, Joshua
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229435/
https://ncbi.nlm.nih.gov/pubmed/9806965
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