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Interactions of a Reversible Ryanoid (21-Amino-9α-Hydroxy-Ryanodine) with Single Sheep Cardiac Ryanodine Receptor Channels

The binding of ryanodine to a high affinity site on the sarcoplasmic reticulum Ca(2+)-release channel results in a dramatic alteration in both gating and ion handling; the channel enters a high open probability, reduced-conductance state. Once bound, ryanodine does not dissociate from its site withi...

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Hlavní autoři: Tanna, Bhavna, Welch, William, Ruest, Luc, Sutko, John L., Williams, Alan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229406/
https://ncbi.nlm.nih.gov/pubmed/9649583
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